Cargando…

Estimating the Cost-Effectiveness of Pre-Exposure Prophylaxis to Reduce HIV-1 and HSV-2 Incidence in HIV-Serodiscordant Couples in South Africa

OBJECTIVE: To estimate the cost-effectiveness of daily oral tenofovir-based PrEP, with a protective effect against HSV-2 as well as HIV-1, among HIV-1 serodiscordant couples in South Africa. METHODS: We incorporated HSV-2 acquisition, transmission, and interaction with HIV-1 into a microsimulation m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jewell, Britta L., Cremin, Ide, Pickles, Michael, Celum, Connie, Baeten, Jared M., Delany-Moretlwe, Sinead, Hallett, Timothy B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304839/ https://www.ncbi.nlm.nih.gov/pubmed/25616135 http://dx.doi.org/10.1371/journal.pone.0115511

Ejemplares similares

Optimal Uses of Antiretrovirals for Prevention in HIV-1 Serodiscordant Heterosexual Couples in South Africa: A Modelling Study
por: Hallett, Timothy B., et al.
Publicado: (2011)

Delivering safer conception services to HIV serodiscordant couples in Kenya: perspectives from healthcare providers and HIV serodiscordant couples
por: Ngure, Kenneth, et al.
Publicado: (2017)

Perceptions of pregnancy occurring among HIV-serodiscordant couples in Kenya
por: Kimemia, Grace, et al.
Publicado: (2019)

Lay Social Resources for Support of Adherence to Antiretroviral Prophylaxis for HIV Prevention Among Serodiscordant Couples in sub-Saharan Africa: A Qualitative Study
por: Ware, Norma C., et al.
Publicado: (2014)

Counseling Framework for HIV-Serodiscordant Couples on the Integrated Use of Antiretroviral Therapy and Pre-exposure Prophylaxis for HIV Prevention
por: Morton, Jennifer F., et al.
Publicado: (2017)

Circumcision of Male Children for Reduction of Future Risk for HIV: Acceptability among HIV Serodiscordant Couples in Kampala, Uganda
por: Mugwanya, Kenneth K., et al.
Publicado: (2011)

HIV pre‐exposure prophylaxis for adolescent girls and young women in Africa: from efficacy trials to delivery
por: Celum, Connie L, et al.
Publicado: (2019)

Adherence to Antiretroviral Prophylaxis for HIV Prevention: A Substudy Cohort within a Clinical Trial of Serodiscordant Couples in East Africa
por: Haberer, Jessica E., et al.
Publicado: (2013)

Integrated delivery of antiretroviral treatment and pre‐exposure prophylaxis to HIV‐1 serodiscordant couples in East Africa: a qualitative evaluation study in Uganda
por: Ware, Norma C, et al.
Publicado: (2018)

Estimating the impact of universal antiretroviral therapy for HIV serodiscordant couples through home HIV testing: insights from mathematical models
por: Roberts, Sarah T, et al.
Publicado: (2016)

Mortality in members of HIV-1 serodiscordant couples in Africa and implications for antiretroviral therapy initiation: Results of analyses from a multicenter randomized trial
por: de Bruyn, Guy, et al.
Publicado: (2012)

The Incremental Cost of Delivering PrEP as a Bridge to ART for HIV Serodiscordant Couples in Public HIV Care Clinics in Kenya
por: Irungu, Elizabeth M., et al.
Publicado: (2019)

Sexual Behaviors After PrEP Discontinuation Among HIV Serodiscordant Couples in Kenya and Uganda
por: Stalter, Randy, et al.
Publicado: (2020)

Beyond HIV prevention: everyday life priorities and demand for PrEP among Ugandan HIV serodiscordant couples
por: Nakku‐Joloba, Edith, et al.
Publicado: (2019)

Alignment of adherence and risk for HIV acquisition in a demonstration project of pre-exposure prophylaxis among HIV serodiscordant couples in Kenya and Uganda: a prospective analysis of prevention-effective adherence
por: Haberer, Jessica E., et al.
Publicado: (2017)

Investing in the future: lessons learnt from communicating the results of HSV/ HIV intervention trials in South Africa
por: Delany-Moretlwe, Sinead, et al.
Publicado: (2011)

Adherence to recommendations for ART and targeted PrEP use among HIV serodiscordant couples in East Africa: the “PrEP as a bridge to ART” strategy
por: Musinguzi, Nicholas, et al.
Publicado: (2020)

No Evidence of Sexual Risk Compensation Following PrEP Initiation Among Heterosexual HIV Serodiscordant Couples in Kenya and Uganda
por: Ortblad, Katrina F., et al.
Publicado: (2019)

Risk Factors for HSV-2 Infection among Sexual Partners of HSV-2/HIV-1 Co-Infected Persons
por: Mujugira, Andrew, et al.
Publicado: (2011)

Characteristics of HIV-1 Serodiscordant Couples Enrolled in a Clinical Trial of Antiretroviral Pre-Exposure Prophylaxis for HIV-1 Prevention
por: Mujugira, Andrew, et al.
Publicado: (2011)

Cost-effectiveness of pre-exposure prophylaxis targeted to high-risk serodiscordant couples as a bridge to sustained ART use in Kampala, Uganda
por: Ying, Roger, et al.
Publicado: (2015)

Use of a risk scoring tool to identify higher-risk HIV-1 serodiscordant couples for an antiretroviral-based HIV-1 prevention intervention
por: Irungu, Elizabeth M., et al.
Publicado: (2016)

Preventing HIV among adolescents with oral PrEP: observations and challenges in the United States and South Africa
por: Hosek, Sybil, et al.
Publicado: (2016)

Intimate Partner Violence and Adherence to HIV Pre-exposure Prophylaxis (PrEP) in African Women in HIV Serodiscordant Relationships: A Prospective Cohort Study
por: Roberts, Sarah T., et al.
Publicado: (2016)

Integrated Delivery of Antiretroviral Treatment and Pre-exposure Prophylaxis to HIV-1–Serodiscordant Couples: A Prospective Implementation Study in Kenya and Uganda
por: Baeten, Jared M., et al.
Publicado: (2016)

‘It’s not about money, it’s about my health’: determinants of participation and adherence among women in an HIV-HSV2 prevention trial in Johannesburg, South Africa
por: MacPhail, Catherine, et al.
Publicado: (2012)

Implementation of a comprehensive safer conception intervention for HIV‐serodiscordant couples in Kenya: uptake, use and effectiveness
por: Heffron, Renee, et al.
Publicado: (2019)

A Scoring Tool to Identify East African HIV-1 Serodiscordant Partnerships with a High Likelihood of Pregnancy
por: Heffron, Renee, et al.
Publicado: (2015)

Adaptive HIV pre-exposure prophylaxis adherence interventions for young South African women: Study protocol for a sequential multiple assignment randomized trial
por: Velloza, Jennifer, et al.
Publicado: (2022)

Genomewide Association Study for Determinants of HIV-1 Acquisition and Viral Set Point in HIV-1 Serodiscordant Couples with Quantified Virus Exposure
por: Lingappa, Jairam R., et al.
Publicado: (2011)

Rethinking HIV prevention to prepare for oral PrEP implementation for young African women
por: Celum, Connie L, et al.
Publicado: (2015)

Psychosocial support for HIV serodiscordant couples
por: Lelaka, Constance Matshidiso, et al.
Publicado: (2022)

Correction: Genomewide Association Study for Determinants of HIV-1 Acquisition and Viral Set Point in HIV-1 Serodiscordant Couples with Quantified Virus Exposure
por: Lingappa, Jairam R., et al.
Publicado: (2012)

Assessing longitudinal patterns of depressive symptoms and the influence of symptom trajectories on HIV pre‐exposure prophylaxis adherence among adolescent girls in the HPTN 082 randomized controlled trial
por: Velloza, Jennifer, et al.
Publicado: (2021)

Alloimmunity to Class 2 Human Leucocyte Antigens May Reduce HIV-1 Acquisition – A Nested Case-Control Study in HIV-1 Serodiscordant Couples
por: Suchard, Melinda S., et al.
Publicado: (2022)

Regional Differences in Prevalence of HIV-1 Discordance in Africa and Enrollment of HIV-1 Discordant Couples into an HIV-1 Prevention Trial
por: Lingappa, Jairam R., et al.
Publicado: (2008)

Knowledge of HIV Serodiscordance, Transmission, and Prevention among Couples in Durban, South Africa
por: Kilembe, William, et al.
Publicado: (2015)

Intimate partner violence among HIV-serodiscordant couples in Durban, South Africa
por: Mashaphu, S, et al.
Publicado: (2018)

Pre-exposure prophylaxis use among HIV serodiscordant couples: a qualitative study in Mozambique
por: Sack, Daniel E., et al.
Publicado: (2021)

Supporting people living with HIV in serodiscordant partnerships to attempt a desired pregnancy by integrating sexual and reproductive health and HIV interventions
por: Narasimhan, Manjulaa, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jai7jlr33sjjtmjijfhrrlrsj1