Antagonizing Bcl-2 Family Members Sensitizes Neuroblastoma and Ewing’s Sarcoma to an Inhibitor of Glutamine Metabolism

Neuroblastomas (NBL) and Ewing’s sarcomas (EWS) together cause 18% of all pediatric cancer deaths. Though there is growing interest in targeting the dysregulated metabolism of cancer as a therapeutic strategy, this approach has not been fully examined in NBL and EWS. In this study, we first tested a...

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Detalles Bibliográficos
Autores principales: Olsen, Rachelle R., Mary-Sinclair, Michelle N., Yin, Zhirong, Freeman, Kevin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304844/
https://www.ncbi.nlm.nih.gov/pubmed/25615615
http://dx.doi.org/10.1371/journal.pone.0116998

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