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The many weak instruments problem and Mendelian randomization

Instrumental variable estimates of causal effects can be biased when using many instruments that are only weakly associated with the exposure. We describe several techniques to reduce this bias and estimate corrected standard errors. We present our findings using a simulation study and an empirical...

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Detalles Bibliográficos
Autores principales:	Davies, Neil M, von Hinke Kessler Scholder, Stephanie, Farbmacher, Helmut, Burgess, Stephen, Windmeijer, Frank, Smith, George Davey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305205/ https://www.ncbi.nlm.nih.gov/pubmed/25382280 http://dx.doi.org/10.1002/sim.6358

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