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Hyperdiploidy associated with T315I mutation in BCR-ABL kinase domain in an accelerated phase-chronic myeloid leukemia case

BACKGROUND: Chronic myeloid leukemia (CML) is genetically characterized by the occurrence of a reciprocal translocation t(9;22)(q34;q11), resulting in a BCR/ABL gene fusion on the derivative chromosome 22, i.e. the Philadelphia (Ph) chromosome. During CML progression 60–80% of the cases acquire addi...

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Detalles Bibliográficos
Autores principales:	Al-Achkar, Walid, Moassass, Faten, Ikhtiar, Adnan, Liehr, Thomas, Othman, Moneeb Abdullah Kassem, Wafa, Abdulsamad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305221/ https://www.ncbi.nlm.nih.gov/pubmed/25621010 http://dx.doi.org/10.1186/s13039-014-0089-0

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