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Cancer progression by breast tumors with Pit-1-overexpression is blocked by inhibition of metalloproteinase (MMP)-13
INTRODUCTION: The POU class 1 homeobox 1 transcription factor (POU1F1, also known as Pit-1) is expressed in the mammary gland and its overexpression induces profound phenotypic changes in proteins involved in cell proliferation, apoptosis, and invasion. Patients with breast cancer and elevated expre...
Autores principales: | Sendon-Lago, Juan, Seoane, Samuel, Eiro, Noemi, Bermudez, Maria A, Macia, Manuel, Garcia-Caballero, Tomas, Vizoso, Francisco J, Perez-Fernandez, Roman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305241/ https://www.ncbi.nlm.nih.gov/pubmed/25527274 http://dx.doi.org/10.1186/s13058-014-0505-8 |
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