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Swelling/Floating Capability and Drug Release Characterizations of Gastroretentive Drug Delivery System Based on a Combination of Hydroxyethyl Cellulose and Sodium Carboxymethyl Cellulose

The aim of this study was to characterize the swelling and floating behaviors of gastroretentive drug delivery system (GRDDS) composed of hydroxyethyl cellulose (HEC) and sodium carboxymethyl cellulose (NaCMC) and to optimize HEC/NaCMC GRDDS to incorporate three model drugs with different solubiliti...

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Detalles Bibliográficos
Autores principales: Chen, Ying-Chen, Ho, Hsiu-O, Liu, Der-Zen, Siow, Wen-Shian, Sheu, Ming-Thau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305323/
https://www.ncbi.nlm.nih.gov/pubmed/25617891
http://dx.doi.org/10.1371/journal.pone.0116914