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The nuclear receptor NR2E1/TLX controls senescence

The nuclear receptor NR2E1 (also known as TLX or tailless) controls the self-renewal of neural stem cells (NSCs) and has been implied as an oncogene which initiates brain tumours including glioblastomas. Despite NR2E1 regulating targets like p21(CIP1) or PTEN we still lack a full explanation for its...

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Detalles Bibliográficos
Autores principales:	O’Loghlen, Ana, Martin, Nadine, Krusche, Benjamin, Pemberton, Helen, Alonso, Marta M., Chandler, Hollie, Brookes, Sharon, Parrinello, Simona, Peters, Gordon, Gil, Jesús
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305339/ https://www.ncbi.nlm.nih.gov/pubmed/25328137 http://dx.doi.org/10.1038/onc.2014.335

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