Transcription-coupled recruitment of human CHD1 and CHD2 influences chromatin accessibility and histone H3 and H3.3 occupancy at active chromatin regions

BACKGROUND: CHD1 and CHD2 chromatin remodeling enzymes play important roles in development, cancer and differentiation. At a molecular level, the mechanisms are not fully understood but include transcriptional regulation, nucleosome organization and turnover. RESULTS: Here we show human CHD1 and CHD...

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Detalles Bibliográficos
Autores principales: Siggens, Lee, Cordeddu, Lina, Rönnerblad, Michelle, Lennartsson, Andreas, Ekwall, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305392/
https://www.ncbi.nlm.nih.gov/pubmed/25621013
http://dx.doi.org/10.1186/1756-8935-8-4

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