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Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease
Aim. To evaluate the results of temporary fecal diversion in colorectal and perianal Crohn's disease. Method. We retrospectively identified 29 consecutive patients (14 females, 15 males; median age: 30.0 years, range: 18–76) undergoing temporary fecal diversion for colorectal (n = 14), ileal (n...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305613/ https://www.ncbi.nlm.nih.gov/pubmed/25649893 http://dx.doi.org/10.1155/2015/286315 |
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author | Mennigen, Rudolf Heptner, Britta Senninger, Norbert Rijcken, Emile |
author_facet | Mennigen, Rudolf Heptner, Britta Senninger, Norbert Rijcken, Emile |
author_sort | Mennigen, Rudolf |
collection | PubMed |
description | Aim. To evaluate the results of temporary fecal diversion in colorectal and perianal Crohn's disease. Method. We retrospectively identified 29 consecutive patients (14 females, 15 males; median age: 30.0 years, range: 18–76) undergoing temporary fecal diversion for colorectal (n = 14), ileal (n = 4), and/or perianal Crohn's disease (n = 22). Follow-up was in median 33.0 (3–103) months. Response to fecal diversion, rate of stoma reversal, and relapse rate after stoma reversal were recorded. Results. The response to temporary fecal diversion was complete remission in 4/29 (13.8%), partial remission in 12/29 (41.4%), no change in 7/29 (24.1%), and progress in 6/29 (20.7%). Stoma reversal was performed in 19 out of 25 patients (76%) available for follow-up. Of these, the majority (15/19, 78.9%) needed further surgical therapies for a relapse of the same pathology previously leading to temporary fecal diversion, including colorectal resections (10/19, 52.6%) and creation of a definitive stoma (7/19, 36.8%). At the end of follow-up, only 4/25 patients (16%) had a stable course without the need for further definitive surgery. Conclusion. Temporary fecal diversion can induce remission in otherwise refractory colorectal or perianal Crohn's disease, but the chance of enduring remission after stoma reversal is low. |
format | Online Article Text |
id | pubmed-4305613 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43056132015-02-03 Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease Mennigen, Rudolf Heptner, Britta Senninger, Norbert Rijcken, Emile Gastroenterol Res Pract Research Article Aim. To evaluate the results of temporary fecal diversion in colorectal and perianal Crohn's disease. Method. We retrospectively identified 29 consecutive patients (14 females, 15 males; median age: 30.0 years, range: 18–76) undergoing temporary fecal diversion for colorectal (n = 14), ileal (n = 4), and/or perianal Crohn's disease (n = 22). Follow-up was in median 33.0 (3–103) months. Response to fecal diversion, rate of stoma reversal, and relapse rate after stoma reversal were recorded. Results. The response to temporary fecal diversion was complete remission in 4/29 (13.8%), partial remission in 12/29 (41.4%), no change in 7/29 (24.1%), and progress in 6/29 (20.7%). Stoma reversal was performed in 19 out of 25 patients (76%) available for follow-up. Of these, the majority (15/19, 78.9%) needed further surgical therapies for a relapse of the same pathology previously leading to temporary fecal diversion, including colorectal resections (10/19, 52.6%) and creation of a definitive stoma (7/19, 36.8%). At the end of follow-up, only 4/25 patients (16%) had a stable course without the need for further definitive surgery. Conclusion. Temporary fecal diversion can induce remission in otherwise refractory colorectal or perianal Crohn's disease, but the chance of enduring remission after stoma reversal is low. Hindawi Publishing Corporation 2015 2015-01-11 /pmc/articles/PMC4305613/ /pubmed/25649893 http://dx.doi.org/10.1155/2015/286315 Text en Copyright © 2015 Rudolf Mennigen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Mennigen, Rudolf Heptner, Britta Senninger, Norbert Rijcken, Emile Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease |
title | Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease |
title_full | Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease |
title_fullStr | Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease |
title_full_unstemmed | Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease |
title_short | Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease |
title_sort | temporary fecal diversion in the management of colorectal and perianal crohn's disease |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305613/ https://www.ncbi.nlm.nih.gov/pubmed/25649893 http://dx.doi.org/10.1155/2015/286315 |
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