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Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease

Aim. To evaluate the results of temporary fecal diversion in colorectal and perianal Crohn's disease. Method. We retrospectively identified 29 consecutive patients (14 females, 15 males; median age: 30.0 years, range: 18–76) undergoing temporary fecal diversion for colorectal (n = 14), ileal (n...

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Autores principales: Mennigen, Rudolf, Heptner, Britta, Senninger, Norbert, Rijcken, Emile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305613/
https://www.ncbi.nlm.nih.gov/pubmed/25649893
http://dx.doi.org/10.1155/2015/286315
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author Mennigen, Rudolf
Heptner, Britta
Senninger, Norbert
Rijcken, Emile
author_facet Mennigen, Rudolf
Heptner, Britta
Senninger, Norbert
Rijcken, Emile
author_sort Mennigen, Rudolf
collection PubMed
description Aim. To evaluate the results of temporary fecal diversion in colorectal and perianal Crohn's disease. Method. We retrospectively identified 29 consecutive patients (14 females, 15 males; median age: 30.0 years, range: 18–76) undergoing temporary fecal diversion for colorectal (n = 14), ileal (n = 4), and/or perianal Crohn's disease (n = 22). Follow-up was in median 33.0 (3–103) months. Response to fecal diversion, rate of stoma reversal, and relapse rate after stoma reversal were recorded. Results. The response to temporary fecal diversion was complete remission in 4/29 (13.8%), partial remission in 12/29 (41.4%), no change in 7/29 (24.1%), and progress in 6/29 (20.7%). Stoma reversal was performed in 19 out of 25 patients (76%) available for follow-up. Of these, the majority (15/19, 78.9%) needed further surgical therapies for a relapse of the same pathology previously leading to temporary fecal diversion, including colorectal resections (10/19, 52.6%) and creation of a definitive stoma (7/19, 36.8%). At the end of follow-up, only 4/25 patients (16%) had a stable course without the need for further definitive surgery. Conclusion. Temporary fecal diversion can induce remission in otherwise refractory colorectal or perianal Crohn's disease, but the chance of enduring remission after stoma reversal is low.
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spelling pubmed-43056132015-02-03 Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease Mennigen, Rudolf Heptner, Britta Senninger, Norbert Rijcken, Emile Gastroenterol Res Pract Research Article Aim. To evaluate the results of temporary fecal diversion in colorectal and perianal Crohn's disease. Method. We retrospectively identified 29 consecutive patients (14 females, 15 males; median age: 30.0 years, range: 18–76) undergoing temporary fecal diversion for colorectal (n = 14), ileal (n = 4), and/or perianal Crohn's disease (n = 22). Follow-up was in median 33.0 (3–103) months. Response to fecal diversion, rate of stoma reversal, and relapse rate after stoma reversal were recorded. Results. The response to temporary fecal diversion was complete remission in 4/29 (13.8%), partial remission in 12/29 (41.4%), no change in 7/29 (24.1%), and progress in 6/29 (20.7%). Stoma reversal was performed in 19 out of 25 patients (76%) available for follow-up. Of these, the majority (15/19, 78.9%) needed further surgical therapies for a relapse of the same pathology previously leading to temporary fecal diversion, including colorectal resections (10/19, 52.6%) and creation of a definitive stoma (7/19, 36.8%). At the end of follow-up, only 4/25 patients (16%) had a stable course without the need for further definitive surgery. Conclusion. Temporary fecal diversion can induce remission in otherwise refractory colorectal or perianal Crohn's disease, but the chance of enduring remission after stoma reversal is low. Hindawi Publishing Corporation 2015 2015-01-11 /pmc/articles/PMC4305613/ /pubmed/25649893 http://dx.doi.org/10.1155/2015/286315 Text en Copyright © 2015 Rudolf Mennigen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mennigen, Rudolf
Heptner, Britta
Senninger, Norbert
Rijcken, Emile
Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease
title Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease
title_full Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease
title_fullStr Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease
title_full_unstemmed Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease
title_short Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn's Disease
title_sort temporary fecal diversion in the management of colorectal and perianal crohn's disease
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305613/
https://www.ncbi.nlm.nih.gov/pubmed/25649893
http://dx.doi.org/10.1155/2015/286315
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