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Exploring the spatial dimension of estrogen and progesterone signaling: detection of nuclear labeling in lobular epithelial cells in normal mammary glands adjacent to breast cancer

BACKGROUND: Comprehensive spatial assessment of hormone receptor immunohistochemistry staining in digital whole slide images of breast cancer requires accurate detection of positive nuclei within biologically relevant regions of interest. Herein, we propose a combination of automated region labeling...

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Detalles Bibliográficos
Autores principales:	Grote, Anne, Abbas, Mahmoud, Linder, Nina, Kreipe, Hans H, Lundin, Johan, Feuerhake, Friedrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305969/ https://www.ncbi.nlm.nih.gov/pubmed/25565114 http://dx.doi.org/10.1186/1746-1596-9-S1-S11

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