A Novel Anti-Histone H1 Monoclonal Antibody, SSV Monoclonal Antibody, Improves Lung Injury and Survival in a Mouse Model of Lipopolysaccharide-Induced Sepsis-Like Syndrome

Background. Histones play important roles in both host defenses and inflammation related to microbial infection. A peptide mimotope (SSV) was identified from a novel histone H1 monoclonal antibody (16G9 mAb) that was shown to inhibit the mixed lymphocyte reaction. In the present study, an anti-SSV p...

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Detalles Bibliográficos
Autores principales: Kusano, Toru, Chiang, Kuei-Chen, Inomata, Masafumi, Shimada, Yayoi, Ohmori, Naoya, Goto, Takeshi, Sato, Shuji, Goto, Shigeru, Nakano, Toshiaki, Kawamoto, Seiji, Takaoka, Yuki, Shiraishi, Norio, Noguchi, Takayuki, Kitano, Seigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306253/
https://www.ncbi.nlm.nih.gov/pubmed/25649890
http://dx.doi.org/10.1155/2015/491649

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