BKCa channel inhibitor modulates the tumorigenic ability of hormone-independent breast cancer cells via the Wnt pathway

In breast cancers, the large conductance Ca(2+) and voltage sensitive K(+) (BKCa) channels have been hypothesized to function as oncoproteins, yet it remains unclear how inhibition of channel activity impacts oncogenesis. We demonstrated herein that iberiotoxin (IbTX), an inhibitor of BKCa channels,...

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Detalles Bibliográficos
Autores principales: SCHICKLING, BRANDON M., ENGLAND, SARAH K., AYKIN-BURNS, NUKHET, NORIAN, LYSE A., LESLIE, KIMBERLY K., FRIEDEN-KOROVKINA, VICTORIA P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306270/
https://www.ncbi.nlm.nih.gov/pubmed/25422049
http://dx.doi.org/10.3892/or.2014.3617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306270/
https://www.ncbi.nlm.nih.gov/pubmed/25422049
http://dx.doi.org/10.3892/or.2014.3617

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