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Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas
CYP27B1 hydroxylates 25-hydroxyvitamin D(3) in position C1α into biologically active 1,25-dihydroxyvitamin D(3), calcitriol. CYP27B1 is expressed in normal tissues and tumors. Since calcitriol indicates anticancer activities and CYP27B1 expression can be deregulated during malignant progression, we...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306272/ https://www.ncbi.nlm.nih.gov/pubmed/25501638 http://dx.doi.org/10.3892/or.2014.3666 |