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Dose Response of Endotoxin on Hepatocyte and Muscle Mitochondrial Respiration In Vitro

Introduction. Results on mitochondrial dysfunction in sepsis are controversial. We aimed to assess effects of LPS at wide dose and time ranges on hepatocytes and isolated skeletal muscle mitochondria. Methods. Human hepatocellular carcinoma cells (HepG2) were exposed to placebo or LPS (0.1, 1, and 1...

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Detalles Bibliográficos
Autores principales: Jeger, Victor, Brandt, Sebastian, Porta, Francesca, Jakob, Stephan M., Takala, Jukka, Djafarzadeh, Siamak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306363/
https://www.ncbi.nlm.nih.gov/pubmed/25649304
http://dx.doi.org/10.1155/2015/353074