Cargando…

New Prognostic Score for the Prediction of 30-Day Outcome in Spontaneous Supratentorial Cerebral Haemorrhage

Aims. The purpose of the present study was to evaluate predictors of outcome in primary supratentorial cerebral haemorrhage. Furthermore, we aimed to develop a prognostic model to predict 30-day fatality. Methods. We retrospectively analyzed a database of 156 patients with spontaneous supratentorial...

Descripción completa

Detalles Bibliográficos
Autores principales: Szepesi, Rita, Széll, Ibolya Katalin, Hortobágyi, Tibor, Kardos, László, Nagy, Katalin, Lánczi, Levente István, Berényi, Ervin, Bereczki, Dániel, Csiba, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306393/
https://www.ncbi.nlm.nih.gov/pubmed/25648158
http://dx.doi.org/10.1155/2015/961085
_version_ 1782354321287938048
author Szepesi, Rita
Széll, Ibolya Katalin
Hortobágyi, Tibor
Kardos, László
Nagy, Katalin
Lánczi, Levente István
Berényi, Ervin
Bereczki, Dániel
Csiba, László
author_facet Szepesi, Rita
Széll, Ibolya Katalin
Hortobágyi, Tibor
Kardos, László
Nagy, Katalin
Lánczi, Levente István
Berényi, Ervin
Bereczki, Dániel
Csiba, László
author_sort Szepesi, Rita
collection PubMed
description Aims. The purpose of the present study was to evaluate predictors of outcome in primary supratentorial cerebral haemorrhage. Furthermore, we aimed to develop a prognostic model to predict 30-day fatality. Methods. We retrospectively analyzed a database of 156 patients with spontaneous supratentorial haemorrhage to explore the relationship between clinical and CT characteristics and fatal outcome within 30 days using multiple logistic regression analysis. The analyzed factors included volumetric data assessed by neuropathological and CT volumetry. A second CT scan in survivors or neuropathological ABC/2 volumetry in nonsurvivors was used along with the baseline CT to assess the growth index of haematoma. Results. Systolic blood pressure, serum potassium and glucose levels, platelet count, absolute and relative haematoma volumes, and presence and size of intraventricular haemorrhage statistically significantly predicted the fatal outcome within 30 days. Based on our results we formulated a six-factor scoring algorithm named SUSPEKT to predict outcome. Conclusions. After validation the SUSPEKT score may be applicable in general clinical practice for early patient selection to optimize individual management or for assessment of eligibility for treatment trials.
format Online
Article
Text
id pubmed-4306393
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-43063932015-02-03 New Prognostic Score for the Prediction of 30-Day Outcome in Spontaneous Supratentorial Cerebral Haemorrhage Szepesi, Rita Széll, Ibolya Katalin Hortobágyi, Tibor Kardos, László Nagy, Katalin Lánczi, Levente István Berényi, Ervin Bereczki, Dániel Csiba, László Biomed Res Int Research Article Aims. The purpose of the present study was to evaluate predictors of outcome in primary supratentorial cerebral haemorrhage. Furthermore, we aimed to develop a prognostic model to predict 30-day fatality. Methods. We retrospectively analyzed a database of 156 patients with spontaneous supratentorial haemorrhage to explore the relationship between clinical and CT characteristics and fatal outcome within 30 days using multiple logistic regression analysis. The analyzed factors included volumetric data assessed by neuropathological and CT volumetry. A second CT scan in survivors or neuropathological ABC/2 volumetry in nonsurvivors was used along with the baseline CT to assess the growth index of haematoma. Results. Systolic blood pressure, serum potassium and glucose levels, platelet count, absolute and relative haematoma volumes, and presence and size of intraventricular haemorrhage statistically significantly predicted the fatal outcome within 30 days. Based on our results we formulated a six-factor scoring algorithm named SUSPEKT to predict outcome. Conclusions. After validation the SUSPEKT score may be applicable in general clinical practice for early patient selection to optimize individual management or for assessment of eligibility for treatment trials. Hindawi Publishing Corporation 2015 2015-01-08 /pmc/articles/PMC4306393/ /pubmed/25648158 http://dx.doi.org/10.1155/2015/961085 Text en Copyright © 2015 Rita Szepesi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Szepesi, Rita
Széll, Ibolya Katalin
Hortobágyi, Tibor
Kardos, László
Nagy, Katalin
Lánczi, Levente István
Berényi, Ervin
Bereczki, Dániel
Csiba, László
New Prognostic Score for the Prediction of 30-Day Outcome in Spontaneous Supratentorial Cerebral Haemorrhage
title New Prognostic Score for the Prediction of 30-Day Outcome in Spontaneous Supratentorial Cerebral Haemorrhage
title_full New Prognostic Score for the Prediction of 30-Day Outcome in Spontaneous Supratentorial Cerebral Haemorrhage
title_fullStr New Prognostic Score for the Prediction of 30-Day Outcome in Spontaneous Supratentorial Cerebral Haemorrhage
title_full_unstemmed New Prognostic Score for the Prediction of 30-Day Outcome in Spontaneous Supratentorial Cerebral Haemorrhage
title_short New Prognostic Score for the Prediction of 30-Day Outcome in Spontaneous Supratentorial Cerebral Haemorrhage
title_sort new prognostic score for the prediction of 30-day outcome in spontaneous supratentorial cerebral haemorrhage
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306393/
https://www.ncbi.nlm.nih.gov/pubmed/25648158
http://dx.doi.org/10.1155/2015/961085
work_keys_str_mv AT szepesirita newprognosticscoreforthepredictionof30dayoutcomeinspontaneoussupratentorialcerebralhaemorrhage
AT szellibolyakatalin newprognosticscoreforthepredictionof30dayoutcomeinspontaneoussupratentorialcerebralhaemorrhage
AT hortobagyitibor newprognosticscoreforthepredictionof30dayoutcomeinspontaneoussupratentorialcerebralhaemorrhage
AT kardoslaszlo newprognosticscoreforthepredictionof30dayoutcomeinspontaneoussupratentorialcerebralhaemorrhage
AT nagykatalin newprognosticscoreforthepredictionof30dayoutcomeinspontaneoussupratentorialcerebralhaemorrhage
AT lanczileventeistvan newprognosticscoreforthepredictionof30dayoutcomeinspontaneoussupratentorialcerebralhaemorrhage
AT berenyiervin newprognosticscoreforthepredictionof30dayoutcomeinspontaneoussupratentorialcerebralhaemorrhage
AT bereczkidaniel newprognosticscoreforthepredictionof30dayoutcomeinspontaneoussupratentorialcerebralhaemorrhage
AT csibalaszlo newprognosticscoreforthepredictionof30dayoutcomeinspontaneoussupratentorialcerebralhaemorrhage