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Molecular Modeling of a Tandem Two Pore Domain Potassium Channel Reveals a Putative Binding Site for General Anesthetics

[Image: see text] Anesthetics are thought to mediate a portion of their activity via binding to and modulation of potassium channels. In particular, tandem pore potassium channels (K2P) are transmembrane ion channels whose current is modulated by the presence of general anesthetics and whose genetic...

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Detalles Bibliográficos
Autores principales:	Bertaccini, Edward J., Dickinson, Robert, Trudell, James R., Franks, Nicholas P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306477/ https://www.ncbi.nlm.nih.gov/pubmed/25340635 http://dx.doi.org/10.1021/cn500172e

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