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Compartment-Specific and Sequential Role of MyD88 and CARD9 in Chemokine Induction and Innate Defense during Respiratory Fungal Infection

Aspergillus fumigatus forms ubiquitous airborne conidia that humans inhale on a daily basis. Although respiratory fungal infection activates the adaptor proteins CARD9 and MyD88 via C-type lectin, Toll-like, and interleukin-1 family receptor signals, defining the temporal and spatial pattern of MyD8...

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Detalles Bibliográficos
Autores principales: Jhingran, Anupam, Kasahara, Shinji, Shepardson, Kelly M., Junecko, Beth A. Fallert, Heung, Lena J., Kumasaka, Debra K., Knoblaugh, Sue E., Lin, Xin, Kazmierczak, Barbara I., Reinhart, Todd A., Cramer, Robert A., Hohl, Tobias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306481/
https://www.ncbi.nlm.nih.gov/pubmed/25621893
http://dx.doi.org/10.1371/journal.ppat.1004589