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Compartment-Specific and Sequential Role of MyD88 and CARD9 in Chemokine Induction and Innate Defense during Respiratory Fungal Infection
Aspergillus fumigatus forms ubiquitous airborne conidia that humans inhale on a daily basis. Although respiratory fungal infection activates the adaptor proteins CARD9 and MyD88 via C-type lectin, Toll-like, and interleukin-1 family receptor signals, defining the temporal and spatial pattern of MyD8...
Autores principales: | Jhingran, Anupam, Kasahara, Shinji, Shepardson, Kelly M., Junecko, Beth A. Fallert, Heung, Lena J., Kumasaka, Debra K., Knoblaugh, Sue E., Lin, Xin, Kazmierczak, Barbara I., Reinhart, Todd A., Cramer, Robert A., Hohl, Tobias M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306481/ https://www.ncbi.nlm.nih.gov/pubmed/25621893 http://dx.doi.org/10.1371/journal.ppat.1004589 |
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