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On the Subjective Acceptance during Cardiovascular Magnetic Resonance Imaging at 7.0 Tesla

PURPOSE: This study examines the subjective acceptance during UHF-CMR in a cohort of healthy volunteers who underwent a cardiac MR examination at 7.0T. METHODS: Within a period of two-and-a-half years (January 2012 to June 2014) a total of 165 healthy volunteers (41 female, 124 male) without any kno...

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Autores principales: Klix, Sabrina, Els, Antje, Paul, Katharina, Graessl, Andreas, Oezerdem, Celal, Weinberger, Oliver, Winter, Lukas, Thalhammer, Christof, Huelnhagen, Till, Rieger, Jan, Mehling, Heidrun, Schulz-Menger, Jeanette, Niendorf, Thoralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306482/
https://www.ncbi.nlm.nih.gov/pubmed/25621491
http://dx.doi.org/10.1371/journal.pone.0117095
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author Klix, Sabrina
Els, Antje
Paul, Katharina
Graessl, Andreas
Oezerdem, Celal
Weinberger, Oliver
Winter, Lukas
Thalhammer, Christof
Huelnhagen, Till
Rieger, Jan
Mehling, Heidrun
Schulz-Menger, Jeanette
Niendorf, Thoralf
author_facet Klix, Sabrina
Els, Antje
Paul, Katharina
Graessl, Andreas
Oezerdem, Celal
Weinberger, Oliver
Winter, Lukas
Thalhammer, Christof
Huelnhagen, Till
Rieger, Jan
Mehling, Heidrun
Schulz-Menger, Jeanette
Niendorf, Thoralf
author_sort Klix, Sabrina
collection PubMed
description PURPOSE: This study examines the subjective acceptance during UHF-CMR in a cohort of healthy volunteers who underwent a cardiac MR examination at 7.0T. METHODS: Within a period of two-and-a-half years (January 2012 to June 2014) a total of 165 healthy volunteers (41 female, 124 male) without any known history of cardiac disease underwent UHF-CMR. For the assessment of the subjective acceptance a questionnaire was used to examine the participants experience prior, during and after the UHF-CMR examination. For this purpose, subjects were asked to respond to the questionnaire in an exit interview held immediately after the completion of the UHF-CMR examination under supervision of a study nurse to ensure accurate understanding of the questions. All questions were answered with “yes” or “no” including space for additional comments. RESULTS: Transient muscular contraction was documented in 12.7% of the questionnaires. Muscular contraction was reported to occur only during periods of scanning with the magnetic field gradients being rapidly switched. Dizziness during the study was reported by 12.7% of the subjects. Taste of metal was reported by 10.1% of the study population. Light flashes were reported by 3.6% of the entire cohort. 13% of the subjects reported side effects/observations which were not explicitly listed in the questionnaire but covered by the question about other side effects. No severe side effects as vomiting or syncope after scanning occurred. No increase in heart rate was observed during the UHF-CMR exam versus the baseline clinical examination. CONCLUSIONS: This study adds to the literature by detailing the subjective acceptance of cardiovascular magnetic resonance imaging examinations at a magnetic field strength of 7.0T. Cardiac MR examinations at 7.0T are well tolerated by healthy subjects. Broader observational and multi-center studies including patient cohorts with cardiac diseases are required to gain further insights into the subjective acceptance of UHF-CMR examinations.
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spelling pubmed-43064822015-01-30 On the Subjective Acceptance during Cardiovascular Magnetic Resonance Imaging at 7.0 Tesla Klix, Sabrina Els, Antje Paul, Katharina Graessl, Andreas Oezerdem, Celal Weinberger, Oliver Winter, Lukas Thalhammer, Christof Huelnhagen, Till Rieger, Jan Mehling, Heidrun Schulz-Menger, Jeanette Niendorf, Thoralf PLoS One Research Article PURPOSE: This study examines the subjective acceptance during UHF-CMR in a cohort of healthy volunteers who underwent a cardiac MR examination at 7.0T. METHODS: Within a period of two-and-a-half years (January 2012 to June 2014) a total of 165 healthy volunteers (41 female, 124 male) without any known history of cardiac disease underwent UHF-CMR. For the assessment of the subjective acceptance a questionnaire was used to examine the participants experience prior, during and after the UHF-CMR examination. For this purpose, subjects were asked to respond to the questionnaire in an exit interview held immediately after the completion of the UHF-CMR examination under supervision of a study nurse to ensure accurate understanding of the questions. All questions were answered with “yes” or “no” including space for additional comments. RESULTS: Transient muscular contraction was documented in 12.7% of the questionnaires. Muscular contraction was reported to occur only during periods of scanning with the magnetic field gradients being rapidly switched. Dizziness during the study was reported by 12.7% of the subjects. Taste of metal was reported by 10.1% of the study population. Light flashes were reported by 3.6% of the entire cohort. 13% of the subjects reported side effects/observations which were not explicitly listed in the questionnaire but covered by the question about other side effects. No severe side effects as vomiting or syncope after scanning occurred. No increase in heart rate was observed during the UHF-CMR exam versus the baseline clinical examination. CONCLUSIONS: This study adds to the literature by detailing the subjective acceptance of cardiovascular magnetic resonance imaging examinations at a magnetic field strength of 7.0T. Cardiac MR examinations at 7.0T are well tolerated by healthy subjects. Broader observational and multi-center studies including patient cohorts with cardiac diseases are required to gain further insights into the subjective acceptance of UHF-CMR examinations. Public Library of Science 2015-01-26 /pmc/articles/PMC4306482/ /pubmed/25621491 http://dx.doi.org/10.1371/journal.pone.0117095 Text en © 2015 Klix et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Klix, Sabrina
Els, Antje
Paul, Katharina
Graessl, Andreas
Oezerdem, Celal
Weinberger, Oliver
Winter, Lukas
Thalhammer, Christof
Huelnhagen, Till
Rieger, Jan
Mehling, Heidrun
Schulz-Menger, Jeanette
Niendorf, Thoralf
On the Subjective Acceptance during Cardiovascular Magnetic Resonance Imaging at 7.0 Tesla
title On the Subjective Acceptance during Cardiovascular Magnetic Resonance Imaging at 7.0 Tesla
title_full On the Subjective Acceptance during Cardiovascular Magnetic Resonance Imaging at 7.0 Tesla
title_fullStr On the Subjective Acceptance during Cardiovascular Magnetic Resonance Imaging at 7.0 Tesla
title_full_unstemmed On the Subjective Acceptance during Cardiovascular Magnetic Resonance Imaging at 7.0 Tesla
title_short On the Subjective Acceptance during Cardiovascular Magnetic Resonance Imaging at 7.0 Tesla
title_sort on the subjective acceptance during cardiovascular magnetic resonance imaging at 7.0 tesla
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306482/
https://www.ncbi.nlm.nih.gov/pubmed/25621491
http://dx.doi.org/10.1371/journal.pone.0117095
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