Cargando…

Dual Peptide Conjugation Strategy for Improved Cellular Uptake and Mitochondria Targeting

[Image: see text] Mitochondria are critical regulators of cellular function and survival. Delivery of therapeutic and diagnostic agents into mitochondria is a challenging task in modern pharmacology because the molecule to be delivered needs to first overcome the cell membrane barrier and then be ab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Ran, Zhang, Pengcheng, Cheetham, Andrew. G., Walston, Jeremy, Abadir, Peter, Cui, Honggang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306504/ https://www.ncbi.nlm.nih.gov/pubmed/25547808 http://dx.doi.org/10.1021/bc500408p

Ejemplares similares

Nature-inspired delivery of mitochondria-targeted angiotensin receptor blocker
por: Phillip, Jude M, et al.
Publicado: (2022)

Enhanced Cellular Entry and Efficacy of Tat Conjugates by Rational Design of the Auxiliary Segment
por: Zhang, Pengcheng, et al.
Publicado: (2014)

Contrasting roles for actin in the cellular uptake of cell penetrating peptide conjugates
por: He, L., et al.
Publicado: (2018)

NGR-peptide−drug conjugates with dual targeting properties
por: Enyedi, Kata Nóra, et al.
Publicado: (2017)

Enhancing cellular uptake of activable cell-penetrating peptide–doxorubicin conjugate by enzymatic cleavage
por: Shi, Nian-Qiu, et al.
Publicado: (2012)

Cooperative Cellular Uptake and Activity of Octaarginine Antisense Peptide Nucleic Acid (PNA) Conjugates
por: Ghavami, Mahdi, et al.
Publicado: (2019)

The impact of age-related dysregulation of the angiotensin system on mitochondrial redox balance
por: Vajapey, Ramya, et al.
Publicado: (2014)

AntimiR-155 Cyclic Peptide–PNA Conjugate: Synthesis, Cellular Uptake, and Biological Activity
por: Soudah, Terese, et al.
Publicado: (2019)

Cellular uptake and anti-tumor activity of gemcitabine conjugated with new amphiphilic cell penetrating peptides
por: Zakeri-Milani, Parvin, et al.
Publicado: (2017)

Sterically Stabilized RIPL Peptide-Conjugated Nanostructured Lipid Carriers: Characterization, Cellular Uptake, Cytotoxicity, and Biodistribution
por: Kim, Chang Hyun, et al.
Publicado: (2018)

Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles
por: Rangger, Christine, et al.
Publicado: (2013)

Rational Design of MMP Degradable Peptide-Based Supramolecular Filaments
por: Lin, Yi-An, et al.
Publicado: (2014)

Mitochondria-Targeted Delivery Strategy of Dual-Loaded Liposomes for Alzheimer’s Disease Therapy
por: Vasileva, Leysan, et al.
Publicado: (2023)

Mitochondria-penetrating peptides conjugated to desferrioxamine as chelators for mitochondrial labile iron
por: Alta, Roxana Y. P., et al.
Publicado: (2017)

A dual-targeting liposome conjugated with transferrin and arginine-glycine-aspartic acid peptide for glioma-targeting therapy
por: QIN, LI, et al.
Publicado: (2014)

Development of novel cyclic NGR peptide–daunomycin conjugates with dual targeting property
por: Tripodi, Andrea Angelo Pierluigi, et al.
Publicado: (2018)

The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)
por: Pharaoh, Gavin, et al.
Publicado: (2023)

Mechanisms of Cellular Uptake of Cell-Penetrating Peptides
por: Madani, Fatemeh, et al.
Publicado: (2011)

Size‐Dependent Cellular Uptake of RGD Peptides
por: Kemker, Isabell, et al.
Publicado: (2019)

Cellular uptake and targeting of low dispersity, dual emissive, segmented block copolymer nanofibers
por: Street, Steven T. G., et al.
Publicado: (2020)

Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives
por: Battogtokh, Gantumur, et al.
Publicado: (2018)

The Dual-Targeted Peptide Conjugated Probe for Depicting Residual Nasopharyngeal Carcinoma and Guiding Surgery
por: Huang, Wenhui, et al.
Publicado: (2022)

Targeting mitochondria as an anticancer strategy
por: Dong, Lanfeng, et al.
Publicado: (2019)

Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake
por: Aviñó, Anna, et al.
Publicado: (2021)

Dual-Targeting Pro-apoptotic Peptide for Programmed Cancer Cell Death via Specific Mitochondria Damage
por: Chen, Wei-Hai, et al.
Publicado: (2013)

Synthesis and characterization of peptide conjugated human serum albumin nanoparticles for targeted cardiac uptake and drug delivery
por: Lomis, Nikita, et al.
Publicado: (2021)

Mitochondria localization induced self-assembly of peptide amphiphiles for cellular dysfunction
por: Jeena, M. T., et al.
Publicado: (2017)

Simultaneous Targeting of Two Master Regulators of Apoptosis with Dual-Action PNA– and DNA–Peptide Conjugates
por: Altrichter, Yannic, et al.
Publicado: (2020)

Both FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution
por: Hou, Zhenqing, et al.
Publicado: (2011)

Synthesis, Characterization, Cellular Uptake, and In Vitro Anticancer Activity of Fullerenol-Doxorubicin Conjugates
por: Xu, Beihua, et al.
Publicado: (2021)

Cell-penetrating artificial mitochondria-targeting peptide-conjugated metallothionein 1A alleviates mitochondrial damage in Parkinson’s disease models
por: Kang, Young Cheol, et al.
Publicado: (2018)

Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction
por: Madreiter-Sokolowski, Corina T., et al.
Publicado: (2018)

Oligohistidine and targeting peptide functionalized TAT-NLS for enhancing cellular uptake and promoting angiogenesis in vivo
por: Li, Qian, et al.
Publicado: (2018)

Development of novel bone targeting peptide–drug conjugate of 13-aminomethyl-15-thiomatrine for osteoporosis therapy
por: Su, Jia, et al.
Publicado: (2021)

Improved Storage Properties and Cellular Uptake of Casticin-Loaded Nanoemulsions Stabilized by Whey Protein-Lactose Conjugate
por: Zhang, Bei, et al.
Publicado: (2021)

Biophysical Determinants for Cellular Uptake of Hydrocarbon-Stapled Peptide Helices
por: Bird, Gregory H., et al.
Publicado: (2016)

Enhanced cellular uptake of lactosomes using cell-penetrating peptides
por: Akahoshi, Akiya, et al.
Publicado: (2016)

Peptides Derived from Angiogenin Regulate Cellular Copper Uptake
por: Tabbì, Giovanni, et al.
Publicado: (2021)

Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides
por: Turner, John J., et al.
Publicado: (2005)

ALTERED TRYPTOPHAN DEGRADATION LINKS CHRONIC INFLAMMATION TO FUNCTIONAL DECLINE & FRAILTY IN MICE AND HUMANS
por: Westbrook, Reyhan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ce82k5oklbc5k68tau05rerttu