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Turning an Aptamer into a Light-Switch Probe with a Single Bioconjugation
[Image: see text] We describe a method for transforming a structure-switching aptamer into a luminescent light-switch probe via a single conjugation. The methodology is demonstrated using a known aptamer for Hg(2+) as a case study. This approach utilizes a lanthanide-based metallointercalator, Eu-DO...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306522/ https://www.ncbi.nlm.nih.gov/pubmed/25427946 http://dx.doi.org/10.1021/bc5003899 |