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PI(5)P Regulates Autophagosome Biogenesis

Phosphatidylinositol 3-phosphate (PI(3)P), the product of class III PI3K VPS34, recruits specific autophagic effectors, like WIPI2, during the initial steps of autophagosome biogenesis and thereby regulates canonical autophagy. However, mammalian cells can produce autophagosomes through enigmatic no...

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Detalles Bibliográficos
Autores principales:	Vicinanza, Mariella, Korolchuk, Viktor I., Ashkenazi, Avraham, Puri, Claudia, Menzies, Fiona M., Clarke, Jonathan H., Rubinsztein, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306530/ https://www.ncbi.nlm.nih.gov/pubmed/25578879 http://dx.doi.org/10.1016/j.molcel.2014.12.007

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