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Topological Models of Heteromeric Protein Assemblies from Mass Spectrometry: Application to the Yeast eIF3:eIF5 Complex

Describing, understanding, and modulating the function of the cell require elucidation of the structures of macromolecular assemblies. Here, we describe an integrative method for modeling heteromeric complexes using as a starting point disassembly pathways determined by native mass spectrometry (MS)...

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Detalles Bibliográficos
Autores principales:	Politis, Argyris, Schmidt, Carla, Tjioe, Elina, Sandercock, Alan M., Lasker, Keren, Gordiyenko, Yuliya, Russel, Daniel, Sali, Andrej, Robinson, Carol V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306531/ https://www.ncbi.nlm.nih.gov/pubmed/25544043 http://dx.doi.org/10.1016/j.chembiol.2014.11.010

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