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A mitochondrial superoxide theory for oxidative stress diseases and aging
Fridovich identified CuZnSOD in 1969 and manganese superoxide dismutase (MnSOD) in 1973, and proposed ”the Superoxide Theory,” which postulates that superoxide (O(2)(•−)) is the origin of most reactive oxygen species (ROS) and that it undergoes a chain reaction in a cell, playing a central role in t...
Autores principales: | Indo, Hiroko P., Yen, Hsiu-Chuan, Nakanishi, Ikuo, Matsumoto, Ken-ichiro, Tamura, Masato, Nagano, Yumiko, Matsui, Hirofumi, Gusev, Oleg, Cornette, Richard, Okuda, Takashi, Minamiyama, Yukiko, Ichikawa, Hiroshi, Suenaga, Shigeaki, Oki, Misato, Sato, Tsuyoshi, Ozawa, Toshihiko, Clair, Daret K. St., Majima, Hideyuki J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306659/ https://www.ncbi.nlm.nih.gov/pubmed/25834301 http://dx.doi.org/10.3164/jcbn.14-42 |
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