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Co-localization of iron binding on silica with p62/sequestosome1 (SQSTM1) in lung granulomas of mice with acute silicosis
The cellular mechanisms involved in the development of silicosis have not been fully elucidated. This study aimed to examine influence of silica-induced lung injury on autophagy. Suspensions of crystalline silica particles were administered transnasally to C57BL/6j mice. Immunohistochemical examinat...
Autores principales: | Shimizu, Yasuo, Dobashi, Kunio, Nagase, Hiroyuki, Ohta, Ken, Sano, Takaaki, Matsuzaki, Shinichi, Ishii, Yoshiki, Satoh, Takahiro, Koka, Masashi, Yokoyama, Akihito, Ohkubo, Takeru, Ishii, Yasuyuki, Kamiya, Tomihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306660/ https://www.ncbi.nlm.nih.gov/pubmed/25834305 http://dx.doi.org/10.3164/jcbn.14-44 |
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