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Co-localization of iron binding on silica with p62/sequestosome1 (SQSTM1) in lung granulomas of mice with acute silicosis

The cellular mechanisms involved in the development of silicosis have not been fully elucidated. This study aimed to examine influence of silica-induced lung injury on autophagy. Suspensions of crystalline silica particles were administered transnasally to C57BL/6j mice. Immunohistochemical examinat...

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Detalles Bibliográficos
Autores principales: Shimizu, Yasuo, Dobashi, Kunio, Nagase, Hiroyuki, Ohta, Ken, Sano, Takaaki, Matsuzaki, Shinichi, Ishii, Yoshiki, Satoh, Takahiro, Koka, Masashi, Yokoyama, Akihito, Ohkubo, Takeru, Ishii, Yasuyuki, Kamiya, Tomihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306660/
https://www.ncbi.nlm.nih.gov/pubmed/25834305
http://dx.doi.org/10.3164/jcbn.14-44

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