The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis

Perlecan is a major heparan sulfate (HS) proteoglycan in the arterial wall. Previous studies have linked it to atherosclerosis. Perlecan contains a core protein and three HS side chains. Its core protein has five domains (DI–DV) with disparate structures and DII is highly homologous to the ligand-bi...

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Detalles Bibliográficos
Autores principales: Xu, Yu-Xin, Ashline, David, Liu, Li, Tassa, Carlos, Shaw, Stanley Y., Ravid, Katya, Layne, Matthew D., Reinhold, Vernon, Robbins, Phillips W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306681/
https://www.ncbi.nlm.nih.gov/pubmed/25528754
http://dx.doi.org/10.1194/jlr.M053017

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