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Relative roles of ABCG5/ABCG8 in liver and intestine

ABCG5 (G5) and ABCG8 (G8) form a sterol transporter that acts in liver and intestine to prevent accumulation of dietary sterols. Mutations in either G5 or G8 cause sitosterolemia, a recessive disorder characterized by sterol accumulation and premature coronary atherosclerosis. Hepatic G5G8 mediates...

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Detalles Bibliográficos
Autores principales:	Wang, Jin, Mitsche, Matthew A., Lütjohann, Dieter, Cohen, Jonathan C., Xie, Xiao-Song, Hobbs, Helen H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306686/ https://www.ncbi.nlm.nih.gov/pubmed/25378657 http://dx.doi.org/10.1194/jlr.M054544

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