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Gating pore currents are defects in common with two Na(v)1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy
The gating pore current, also called omega current, consists of a cation leak through the typically nonconductive voltage-sensor domain (VSD) of voltage-gated ion channels. Although the study of gating pore currents has refined our knowledge of the structure and the function of voltage-gated ion cha...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306709/ https://www.ncbi.nlm.nih.gov/pubmed/25624448 http://dx.doi.org/10.1085/jgp.201411304 |