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Mapping the membrane topography of the TH6–TH7 segment of the diphtheria toxin T-domain channel
Low pH triggers the translocation domain of diphtheria toxin (T-domain), which contains 10 α helices, to insert into a planar lipid bilayer membrane, form a transmembrane channel, and translocate the attached catalytic domain across the membrane. Three T-domain helices, corresponding to TH5, TH8, an...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306713/ https://www.ncbi.nlm.nih.gov/pubmed/25582482 http://dx.doi.org/10.1085/jgp.201411326 |