Cargando…

Could A Deletion in Neuraminidase Stalk Strengthen Human Tropism of the Novel Avian Influenza Virus H7N9 in China, 2013?

Objective. A novel avian influenza A virus (AIV) H7N9 subtype which emerged in China in 2013 caused worldwide concern. Deletion of amino-acids 69 to 73 in the neuraminidase stalk was its most notable characteristic. This study is aimed to discuss the tropism and virulence effects of this deletion. M...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Liang, Zhu, Feng, Xiong, Chenglong, Zhang, Zhijie, Jiang, Lufang, Chen, Yue, Zhao, Genming, Jiang, Qingwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306908/ https://www.ncbi.nlm.nih.gov/pubmed/25608590 http://dx.doi.org/10.3390/ijerph120101020

Ejemplares similares

Emergence and Genetic Variation of Neuraminidase Stalk Deletions in Avian Influenza Viruses
por: Li, Jinling, et al.
Publicado: (2011)

Semiaquatic mammals might be intermediate hosts to spread avian influenza viruses from avian to human
por: Zhao, Ping, et al.
Publicado: (2019)

The complexity of human infected AIV H5N6 isolated from China
por: Zhang, Zhijie, et al.
Publicado: (2016)

The Neuraminidase Stalk Deletion Serves as Major Virulence Determinant of H5N1 Highly Pathogenic Avian Influenza Viruses in Chicken
por: Stech, Olga, et al.
Publicado: (2015)

Microsecond Molecular Dynamics Simulations of Influenza Neuraminidase Suggest a Mechanism for the Increased Virulence of Stalk-Deletion Mutants
por: Durrant, Jacob D., et al.
Publicado: (2016)

Truncation or Deglycosylation of the Neuraminidase Stalk Enhances the Pathogenicity of the H5N1 Subtype Avian Influenza Virus in Mallard Ducks
por: Chen, Sujuan, et al.
Publicado: (2020)

Avian Influenza Virus Tropism in Humans
por: AbuBakar, Umarqayum, et al.
Publicado: (2023)

Biological Characteristics of H9N2 Avian Influenza Viruses from Healthy Chickens in Shanghai, China
por: Shi, Qingfeng, et al.
Publicado: (2016)

A 20-Amino-Acid Deletion in the Neuraminidase Stalk and a Five-Amino-Acid Deletion in the NS1 Protein Both Contribute to the Pathogenicity of H5N1 Avian Influenza Viruses in Mallard Ducks
por: Li, Yanfang, et al.
Publicado: (2014)

Proteome Response of Chicken Embryo Fibroblast Cells to Recombinant H5N1 Avian Influenza Viruses with Different Neuraminidase Stalk Lengths
por: Li, Yongtao, et al.
Publicado: (2017)

Evolutionary interactions between haemagglutinin and neuraminidase in avian influenza
por: Ward, Melissa J, et al.
Publicado: (2013)

Adaptive mutations of neuraminidase stalk truncation and deglycosylation confer enhanced pathogenicity of influenza A viruses
por: Park, Sehee, et al.
Publicado: (2017)

The Special Neuraminidase Stalk-Motif Responsible for Increased Virulence and Pathogenesis of H5N1 Influenza A Virus
por: Zhou, Hongbo, et al.
Publicado: (2009)

The epidemiology of hospitalized influenza in children, a two year population-based study in the People's Republic of China
por: Ji, Wei, et al.
Publicado: (2010)

Enhanced replication of avian-origin H3N2 canine influenza virus in eggs, cell cultures and mice by a two-amino acid insertion in neuraminidase stalk
por: Lin, Yan, et al.
Publicado: (2016)

Effects of oral florfenicol and azithromycin on gut microbiota and adipogenesis in mice
por: Li, Rui, et al.
Publicado: (2017)

Influenza neuraminidase
por: Air, Gillian M.
Publicado: (2011)

Novel antiviral activity of neuraminidase inhibitors against an avian influenza a virus
por: Ushirogawa, Hiroshi, et al.
Publicado: (2011)

Introduction of Cysteines in the Stalk Domain of Recombinant Influenza Virus N1 Neuraminidase Enhances Protein Stability and Immunogenicity in Mice
por: Strohmeier, Shirin, et al.
Publicado: (2021)

Hemagglutinin stalk-binding antibodies enhance effectiveness of neuraminidase inhibitors against influenza via Fc-dependent effector functions
por: Zhang, Ali, et al.
Publicado: (2022)

Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2012–2013
por: Meijer, Adam, et al.
Publicado: (2014)

Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2013–2014
por: Takashita, Emi, et al.
Publicado: (2015)

2D-SAR, Topomer CoMFA and molecular docking studies on avian influenza neuraminidase inhibitors
por: Niu, Bing, et al.
Publicado: (2018)

Biological Characterizations of H5Nx Avian Influenza Viruses Embodying Different Neuraminidases
por: Yu, Yuandi, et al.
Publicado: (2017)

Analysis of hemagglutinin-mediated entry tropism of H5N1 avian influenza
por: Guo, Ying, et al.
Publicado: (2009)

Ensemble-Based Virtual Screening Reveals Potential Novel Antiviral Compounds for Avian Influenza Neuraminidase
por: Cheng, Lily S., et al.
Publicado: (2008)

Neuraminidase Subtyping of Avian Influenza Viruses with PrimerHunter-Designed Primers and Quadruplicate Primer Pools
por: Huang, Yanyan, et al.
Publicado: (2013)

Avian Influenza Virus with Hemagglutinin-Neuraminidase Combination H8N8, Isolated in Russia
por: Sivay, Mariya V., et al.
Publicado: (2014)

Functional neuraminidase inhibitor resistance motifs in avian influenza A(H5Nx) viruses
por: Bialy, Dagmara, et al.
Publicado: (2020)

A Semiquantitative Scoring System for Histopathological and Immunohistochemical Assessment of Lesions and Tissue Tropism in Avian Influenza
por: Landmann, Maria, et al.
Publicado: (2021)

Evolutionary dynamics of the H7N9 avian influenza virus based on large-scale sequence analysis
por: Xiong, Jiasheng, et al.
Publicado: (2019)

A neuraminidase potency assay for quantitative assessment of neuraminidase in influenza vaccines
por: Byrne-Nash, Rose T., et al.
Publicado: (2019)

Consecutive influenza surveillance of neuraminidase mutations and neuraminidase inhibitor resistance in Japan
por: Chong, Yong, et al.
Publicado: (2019)

Correction: Neuraminidase Subtyping of Avian Influenza Viruses with PrimerHunter-Designed Primers and Quadruplicate Primer Pools
por: Huang, Yanyan, et al.
Publicado: (2013)

Multiple Neuraminidase Containing Influenza Virus-like Particle Vaccines Protect Mice from Avian and Human Influenza Virus Infection
por: Kang, Hae-Ji, et al.
Publicado: (2022)

Aurintricarboxylic acid inhibits influenza virus neuraminidase
por: Hung, Hui-Chen, et al.
Publicado: (2009)

Key amino acid position 272 in neuraminidase determines the replication and virulence of H5N6 avian influenza virus in mammals
por: Zhang, Jiahao, et al.
Publicado: (2022)

Nonparametric Evaluation of Dynamic Disease Risk: A Spatio-Temporal Kernel Approach
por: Zhang, Zhijie, et al.
Publicado: (2011)

Avian influenza A/H5N1 neuraminidase expressed in yeast with a functional head domain
por: Yongkiettrakul, S., et al.
Publicado: (2009)

Neuraminidase in Virus-like Particles Contributes to the Protection against High Dose of Avian Influenza Virus Challenge Infection
por: Kang, Hae-Ji, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rfckgcbjk63qqg47lgk7cutq4g