Luciferase Reporter Gene Assay on Human 5-HT Receptor: Which Response Element Should Be Chosen?

Serotonin (5-HT) receptors are valuable molecular targets for antipsychotic drug discovery. Current reported methods for detecting 5-HT receptors, such as cAMP accumulation and calcium influx assay, are often demanding specialized instruments and inconvenient. The luciferase reporter gene assay, bas...

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Detalles Bibliográficos
Autores principales: Chen, Yiming, Xu, Zhongyu, Wu, Dang, Li, Jian, Song, Cheng, Lu, Weiqiang, Huang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306921/
https://www.ncbi.nlm.nih.gov/pubmed/25622827
http://dx.doi.org/10.1038/srep08060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306921/
https://www.ncbi.nlm.nih.gov/pubmed/25622827
http://dx.doi.org/10.1038/srep08060

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