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Luciferase Reporter Gene Assay on Human 5-HT Receptor: Which Response Element Should Be Chosen?
Serotonin (5-HT) receptors are valuable molecular targets for antipsychotic drug discovery. Current reported methods for detecting 5-HT receptors, such as cAMP accumulation and calcium influx assay, are often demanding specialized instruments and inconvenient. The luciferase reporter gene assay, bas...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306921/ https://www.ncbi.nlm.nih.gov/pubmed/25622827 http://dx.doi.org/10.1038/srep08060 |