Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012

Every year, hundreds of new compounds are discovered from the metabolites of marine organisms. Finding new and useful compounds is one of the crucial drivers for this field of research. Here we describe the statistics of bioactive compounds discovered from marine organisms from 1985 to 2012. This wo...

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Detalles Bibliográficos
Autores principales: Hu, Yiwen, Chen, Jiahui, Hu, Guping, Yu, Jianchen, Zhu, Xun, Lin, Yongcheng, Chen, Shengping, Yuan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306932/
https://www.ncbi.nlm.nih.gov/pubmed/25574736
http://dx.doi.org/10.3390/md13010202
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author Hu, Yiwen
Chen, Jiahui
Hu, Guping
Yu, Jianchen
Zhu, Xun
Lin, Yongcheng
Chen, Shengping
Yuan, Jie
author_facet Hu, Yiwen
Chen, Jiahui
Hu, Guping
Yu, Jianchen
Zhu, Xun
Lin, Yongcheng
Chen, Shengping
Yuan, Jie
author_sort Hu, Yiwen
collection PubMed
description Every year, hundreds of new compounds are discovered from the metabolites of marine organisms. Finding new and useful compounds is one of the crucial drivers for this field of research. Here we describe the statistics of bioactive compounds discovered from marine organisms from 1985 to 2012. This work is based on our database, which contains information on more than 15,000 chemical substances including 4196 bioactive marine natural products. We performed a comprehensive statistical analysis to understand the characteristics of the novel bioactive compounds and detail temporal trends, chemical structures, species distribution, and research progress. We hope this meta-analysis will provide useful information for research into the bioactivity of marine natural products and drug development.
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spelling pubmed-43069322015-02-02 Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012 Hu, Yiwen Chen, Jiahui Hu, Guping Yu, Jianchen Zhu, Xun Lin, Yongcheng Chen, Shengping Yuan, Jie Mar Drugs Article Every year, hundreds of new compounds are discovered from the metabolites of marine organisms. Finding new and useful compounds is one of the crucial drivers for this field of research. Here we describe the statistics of bioactive compounds discovered from marine organisms from 1985 to 2012. This work is based on our database, which contains information on more than 15,000 chemical substances including 4196 bioactive marine natural products. We performed a comprehensive statistical analysis to understand the characteristics of the novel bioactive compounds and detail temporal trends, chemical structures, species distribution, and research progress. We hope this meta-analysis will provide useful information for research into the bioactivity of marine natural products and drug development. MDPI 2015-01-07 /pmc/articles/PMC4306932/ /pubmed/25574736 http://dx.doi.org/10.3390/md13010202 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hu, Yiwen
Chen, Jiahui
Hu, Guping
Yu, Jianchen
Zhu, Xun
Lin, Yongcheng
Chen, Shengping
Yuan, Jie
Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012
title Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012
title_full Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012
title_fullStr Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012
title_full_unstemmed Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012
title_short Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012
title_sort statistical research on the bioactivity of new marine natural products discovered during the 28 years from 1985 to 2012
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306932/
https://www.ncbi.nlm.nih.gov/pubmed/25574736
http://dx.doi.org/10.3390/md13010202
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