Isolation and Assessment of the in Vitro Anti-Tumor Activity of Smenothiazole A and B, Chlorinated Thiazole-Containing Peptide/Polyketides from the Caribbean Sponge, Smenospongia aurea

The study of the secondary metabolites contained in the organic extract of Caribbean sponge Smenospongia aurea led to the isolation of smenothiazole A (3) and B (4), hybrid peptide/polyketide compounds. Assays performed using four solid tumor cell lines showed that smenothiazoles exert a potent cyto...

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Detalles Bibliográficos
Autores principales: Esposito, Germana, Teta, Roberta, Miceli, Roberta, Ceccarelli, Luca S., Della Sala, Gerardo, Camerlingo, Rosa, Irollo, Elena, Mangoni, Alfonso, Pirozzi, Giuseppe, Costantino, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306946/
https://www.ncbi.nlm.nih.gov/pubmed/25603342
http://dx.doi.org/10.3390/md13010444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306946/
https://www.ncbi.nlm.nih.gov/pubmed/25603342
http://dx.doi.org/10.3390/md13010444

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