Activation of p53 with Ilimaquinone and Ethylsmenoquinone, Marine Sponge Metabolites, Induces Apoptosis and Autophagy in Colon Cancer Cells

The tumor suppressor, p53, plays an essential role in the cellular response to stress through regulating the expression of genes involved in cell cycle arrest, apoptosis and autophagy. Here, we used a cell-based reporter system for the detection of p53 response transcription to identify the marine s...

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Detalles Bibliográficos
Autores principales: Lee, Hyun-Young, Chung, Kyu Jin, Hwang, In Hyun, Gwak, Jungsuk, Park, Seoyoung, Ju, Bong Gun, Yun, Eunju, Kim, Dong-Eun, Chung, Young-Hwa, Na, MinKyun, Song, Gyu-Yong, Oh, Sangtaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306951/
https://www.ncbi.nlm.nih.gov/pubmed/25603347
http://dx.doi.org/10.3390/md13010543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306951/
https://www.ncbi.nlm.nih.gov/pubmed/25603347
http://dx.doi.org/10.3390/md13010543

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