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Biosynthesis of Akaeolide and Lorneic Acids and Annotation of Type I Polyketide Synthase Gene Clusters in the Genome of Streptomyces sp. NPS554

The incorporation pattern of biosynthetic precursors into two structurally unique polyketides, akaeolide and lorneic acid A, was elucidated by feeding experiments with (13)C-labeled precursors. In addition, the draft genome sequence of the producer, Streptomyces sp. NPS554, was performed and the bio...

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Detalles Bibliográficos
Autores principales:	Zhou, Tao, Komaki, Hisayuki, Ichikawa, Natsuko, Hosoyama, Akira, Sato, Seizo, Igarashi, Yasuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306953/ https://www.ncbi.nlm.nih.gov/pubmed/25603349 http://dx.doi.org/10.3390/md13010581

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