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In vitro reconstruction of branched tubular structures from lung epithelial cells in high cell concentration gradient environment

We have succeeded in developing hollow branching structure in vitro commonly observed in lung airway using primary lung airway epithelial cells. Cell concentration gradient is the key factor that determines production of the branching cellular structures, as optimization of this component removes th...

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Detalles Bibliográficos
Autores principales: Hagiwara, Masaya, Peng, Fei, Ho, Chih-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306969/
https://www.ncbi.nlm.nih.gov/pubmed/25623780
http://dx.doi.org/10.1038/srep08054