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HIV-2 infects resting CD4+ T cells but not monocyte-derived dendritic cells

BACKGROUND: Human Immunodeficiency Virus-type 2 (HIV-2) encodes Vpx that degrades SAMHD1, a cellular restriction factor active in non-dividing cells. HIV-2 replicates in lymphocytes but the susceptibility of monocyte-derived dendritic cells (MDDCs) to in vitro infection remains partly characterized....

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Detalles Bibliográficos
Autores principales:	Chauveau, Lise, Puigdomenech, Isabel, Ayinde, Diana, Roesch, Ferdinand, Porrot, Françoise, Bruni, Daniela, Visseaux, Benoit, Descamps, Diane, Schwartz, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307230/ https://www.ncbi.nlm.nih.gov/pubmed/25582927 http://dx.doi.org/10.1186/s12977-014-0131-7

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