Systemic Delivery of Protein Nanocages Bearing CTT Peptides for Enhanced Imaging of MMP-2 Expression in Metastatic Tumor Models

Matrix metalloproteinase 2 (MMP-2) in metastatic cancer tissue, which is associated with a poor prognosis, is a potential target for tumor imaging in vivo. Here, we describe a metastatic cancer cell-targeted protein nanocage. An MMP-2-binding peptide, termed CTT peptide (CTTHWGFTLC), was conjugated...

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Detalles Bibliográficos
Autores principales: Kawano, Takahito, Murata, Masaharu, Piao, Jing Shu, Narahara, Sayoko, Hamano, Nobuhito, Kang, Jeong-Hun, Hashizume, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307240/
https://www.ncbi.nlm.nih.gov/pubmed/25547485
http://dx.doi.org/10.3390/ijms16010148

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