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USP22 Promotes NSCLC Tumorigenesis via MDMX Up-Regulation and Subsequent p53 Inhibition

Increasing evidence suggests that ubiquitin-specific protease 22 (USP22) has great clinicopathologic significance in oncology. In this study, we investigated the role of USP22 in human NSCLC tumorigenesis along with the underlying mechanisms of action. First, we determined the expression of USP22 in...

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Detalles Bibliográficos
Autores principales:	Ding, Fangbao, Bao, Chunrong, Tian, Yue, Xiao, Haibo, Wang, Mingsong, Xie, Xiao, Hu, Fengqing, Mei, Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307248/ https://www.ncbi.nlm.nih.gov/pubmed/25547493 http://dx.doi.org/10.3390/ijms16010307

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