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Diverse Roles of SIRT1 in Cancer Biology and Lipid Metabolism
SIRT1, an NAD(+)-dependent deacetylase, has been described in the literature as a major player in the regulation of cellular stress responses. Its expression has been shown to be altered in cancer cells, and it targets both histone and non-histone proteins for deacetylation and thereby alters metabo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307284/ https://www.ncbi.nlm.nih.gov/pubmed/25569080 http://dx.doi.org/10.3390/ijms16010950 |