Cargando…
Diverse Roles of SIRT1 in Cancer Biology and Lipid Metabolism
SIRT1, an NAD(+)-dependent deacetylase, has been described in the literature as a major player in the regulation of cellular stress responses. Its expression has been shown to be altered in cancer cells, and it targets both histone and non-histone proteins for deacetylation and thereby alters metabo...
Autores principales: | Simmons, Glenn E., Pruitt, Wendy M., Pruitt, Kevin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307284/ https://www.ncbi.nlm.nih.gov/pubmed/25569080 http://dx.doi.org/10.3390/ijms16010950 |
Ejemplares similares
-
Frizzled 7 Expression Is Positively Regulated by SIRT1 and β-Catenin in Breast Cancer Cells
por: Simmons, Glenn E., et al.
Publicado: (2014) -
A novel MeCP2 acetylation site regulates interaction with ATRX and HDAC1
por: Pandey, Somnath, et al.
Publicado: (2015) -
Targeting lipid metabolism in the treatment of ovarian cancer
por: Chaudhry, Saliha, et al.
Publicado: (2022) -
Inhibition of SIRT1 Reactivates Silenced Cancer Genes without Loss of Promoter DNA Hypermethylation
por: Pruitt, Kevin, et al.
Publicado: (2006) -
Wnt Pathway: An Integral Hub for Developmental and Oncogenic Signaling Networks
por: Sharma, Monica, et al.
Publicado: (2020)