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Elucidating Mechanisms of Toxicity Using Phenotypic Data from Primary Human Cell Systems—A Chemical Biology Approach for Thrombosis-Related Side Effects

Here we describe a chemical biology approach for elucidating potential toxicity mechanisms for thrombosis-related side effects. This work takes advantage of a large chemical biology data set comprising the effects of known, well-characterized reference agents on the cell surface levels of tissue fac...

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Detalles Bibliográficos
Autores principales:	Berg, Ellen L., Polokoff, Mark A., O’Mahony, Alison, Nguyen, Dat, Li, Xitong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307287/ https://www.ncbi.nlm.nih.gov/pubmed/25569083 http://dx.doi.org/10.3390/ijms16011008

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