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Profiling of Ubiquitination Pathway Genes in Peripheral Cells from Patients with Frontotemporal Dementia due to C9ORF72 and GRN Mutations

We analysed the expression levels of 84 key genes involved in the regulated degradation of cellular protein by the ubiquitin-proteasome system in peripheral cells from patients with frontotemporal dementia (FTD) due to C9ORF72 and GRN mutations, as compared with sporadic FTD and age-matched controls...

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Detalles Bibliográficos
Autores principales: Serpente, Maria, Fenoglio, Chiara, Cioffi, Sara M. G., Bonsi, Rossana, Arighi, Andrea, Fumagalli, Giorgio G., Ghezzi, Laura, Scarpini, Elio, Galimberti, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307308/
https://www.ncbi.nlm.nih.gov/pubmed/25580532
http://dx.doi.org/10.3390/ijms16011385