Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore

This paper reports on the synthesis and characterization of two Schiff bases bearing 1,2,4-triazolic moieties, namely 4H-4-(2-hydroxy-benzylidene-amino)-5-benzyl-3-mercapto-1,2,4-triazole and 4H-4-(4-nitro-benzylidene-amino)-5-benzyl-3-mercapto-1,2,4-triazole using thin layer chromatography, melting...

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Detalles Bibliográficos
Autores principales: Ledeţi, Ionuţ, Alexa, Anda, Bercean, Vasile, Vlase, Gabriela, Vlase, Titus, Şuta, Lenuţa-Maria, Fuliaş, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307329/
https://www.ncbi.nlm.nih.gov/pubmed/25590299
http://dx.doi.org/10.3390/ijms16011711
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author Ledeţi, Ionuţ
Alexa, Anda
Bercean, Vasile
Vlase, Gabriela
Vlase, Titus
Şuta, Lenuţa-Maria
Fuliaş, Adriana
author_facet Ledeţi, Ionuţ
Alexa, Anda
Bercean, Vasile
Vlase, Gabriela
Vlase, Titus
Şuta, Lenuţa-Maria
Fuliaş, Adriana
author_sort Ledeţi, Ionuţ
collection PubMed
description This paper reports on the synthesis and characterization of two Schiff bases bearing 1,2,4-triazolic moieties, namely 4H-4-(2-hydroxy-benzylidene-amino)-5-benzyl-3-mercapto-1,2,4-triazole and 4H-4-(4-nitro-benzylidene-amino)-5-benzyl-3-mercapto-1,2,4-triazole using thin layer chromatography, melting interval, elemental analysis, spectroscopy and thermal stability studies.
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spelling pubmed-43073292015-02-02 Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore Ledeţi, Ionuţ Alexa, Anda Bercean, Vasile Vlase, Gabriela Vlase, Titus Şuta, Lenuţa-Maria Fuliaş, Adriana Int J Mol Sci Article This paper reports on the synthesis and characterization of two Schiff bases bearing 1,2,4-triazolic moieties, namely 4H-4-(2-hydroxy-benzylidene-amino)-5-benzyl-3-mercapto-1,2,4-triazole and 4H-4-(4-nitro-benzylidene-amino)-5-benzyl-3-mercapto-1,2,4-triazole using thin layer chromatography, melting interval, elemental analysis, spectroscopy and thermal stability studies. MDPI 2015-01-13 /pmc/articles/PMC4307329/ /pubmed/25590299 http://dx.doi.org/10.3390/ijms16011711 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ledeţi, Ionuţ
Alexa, Anda
Bercean, Vasile
Vlase, Gabriela
Vlase, Titus
Şuta, Lenuţa-Maria
Fuliaş, Adriana
Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore
title Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore
title_full Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore
title_fullStr Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore
title_full_unstemmed Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore
title_short Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore
title_sort synthesis and degradation of schiff bases containing heterocyclic pharmacophore
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307329/
https://www.ncbi.nlm.nih.gov/pubmed/25590299
http://dx.doi.org/10.3390/ijms16011711
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