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A Bayesian prediction model between a biomarker and the clinical endpoint for dichotomous variables
BACKGROUND: Early biomarkers are helpful for predicting clinical endpoints and for evaluating efficacy in clinical trials even if the biomarker cannot replace clinical outcome as a surrogate. The building and evaluation of an association model between biomarkers and clinical outcomes are two equally...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307375/ https://www.ncbi.nlm.nih.gov/pubmed/25528466 http://dx.doi.org/10.1186/1745-6215-15-500 |