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Analysis of pattern overlaps and exact computation of P-values of pattern occurrences numbers: case of Hidden Markov Models
BACKGROUND: Finding new functional fragments in biological sequences is a challenging problem. Methods addressing this problem commonly search for clusters of pattern occurrences that are statistically significant. A measure of statistical significance is the P-value of a number of pattern occurrenc...
Autores principales: | Régnier, Mireille, Furletova, Evgenia, Yakovlev, Victor, Roytberg, Mikhail |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307674/ https://www.ncbi.nlm.nih.gov/pubmed/25648087 http://dx.doi.org/10.1186/s13015-014-0025-1 |
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