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Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid

BACKGROUND: The molecular mechanisms underlying autistic behaviors remain to be elucidated. Mutations in genes linked to autism adversely affect molecules regulating dendritic spine formation, function and plasticity, and some increase the mammalian target of rapamycin, mTOR, a regulator of protein...

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Detalles Bibliográficos
Autores principales:	Nicolini, Chiara, Ahn, Younghee, Michalski, Bernadeta, Rho, Jong M, Fahnestock, Margaret
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307681/ https://www.ncbi.nlm.nih.gov/pubmed/25627160 http://dx.doi.org/10.1186/s40478-015-0184-4

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