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Signaling function of Na,K-ATPase induced by ouabain against LPS as an inflammation model in hippocampus
BACKGROUND: Ouabain (OUA) is a newly recognized hormone that is synthesized in the adrenal cortex and hypothalamus. Low doses of OUA can activate a signaling pathway by interaction with Na,K-ATPase, which is protective against a number of insults. OUA has central and peripheral anti-inflammatory eff...
Autores principales: | Kinoshita, Paula Fernanda, Yshii, Lidia Mitiko, Vasconcelos, Andrea Rodrigues, Orellana, Ana Maria Marques, Lima, Larissa de Sá, Davel, Ana Paula Couto, Rossoni, Luciana Venturini, Kawamoto, Elisa Mitiko, Scavone, Cristoforo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307894/ https://www.ncbi.nlm.nih.gov/pubmed/25551197 http://dx.doi.org/10.1186/s12974-014-0218-z |
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