Cargando…

Investigating the Genetics of Hippocampal Volume in Older Adults without Dementia

Hippocampal atrophy is observed with ageing and age-related neurodegenerative disease. Identification of the genetic correlates of hippocampal volume (HV) and atrophy may assist in elucidating the mechanisms of ageing and age-related neurodegeneration. Using two community cohorts of older Caucasians...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mather, Karen A., Armstrong, Nicola J., Wen, Wei, Kwok, John B., Assareh, Amelia A., Thalamuthu, Anbupalam, Reppermund, Simone, Duesing, Konsta, Wright, Margaret J., Ames, David, Trollor, Julian N., Brodaty, Henry, Schofield, Peter R., Sachdev, Perminder S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308067/ https://www.ncbi.nlm.nih.gov/pubmed/25625606 http://dx.doi.org/10.1371/journal.pone.0116920

Ejemplares similares

Nature Versus Nurture – Studying the Relationships Between Diet and Depression in Older Adults
por: Matison, Annabel, et al.
Publicado: (2022)

Investigating Olfactory Gene Variation and Odour Identification in Older Adults
por: Raj, Siddharth, et al.
Publicado: (2021)

Genetic and environmental influences on fruit and vegetable consumption and depression in older adults
por: Matison, Annabel P., et al.
Publicado: (2023)

Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults
por: Mather, Karen A., et al.
Publicado: (2016)

Genetics of Microstructure of the Corpus Callosum in Older Adults
por: Kanchibhotla, Sri C., et al.
Publicado: (2014)

Microstructural White Matter Changes, Not Hippocampal Atrophy, Detect Early Amnestic Mild Cognitive Impairment
por: Zhuang, Lin, et al.
Publicado: (2013)

Cerebral Blood Flow in Community-Based Older Twins Is Moderately Heritable: An Arterial Spin Labeling Perfusion Imaging Study
por: Jiang, Jiyang, et al.
Publicado: (2019)

The Relationship of Serum Macrophage Inhibitory Cytokine – 1 Levels with Gray Matter Volumes in Community-Dwelling Older Individuals
por: Jiang, Jiyang, et al.
Publicado: (2015)

High polygenic risk score for exceptional longevity is associated with a healthy metabolic profile
por: Revelas, Mary, et al.
Publicado: (2022)

Distinct Genetic Influences on Cortical and Subcortical Brain Structures
por: Wen, Wei, et al.
Publicado: (2016)

Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins
por: Wong, Matthew WK, et al.
Publicado: (2020)

Exceptional Longevity and Polygenic Risk for Cardiovascular Health
por: Revelas, Mary, et al.
Publicado: (2019)

A comparison of machine learning methods for survival analysis of high-dimensional clinical data for dementia prediction
por: Spooner, Annette, et al.
Publicado: (2020)

Age- and Sex-Related Topological Organization of Human Brain Functional Networks and Their Relationship to Cognition
por: Foo, Heidi, et al.
Publicado: (2021)

Risk Factors for Late-Life Cognitive Decline and Variation with Age and Sex in the Sydney Memory and Ageing Study
por: Lipnicki, Darren M., et al.
Publicado: (2013)

Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank
por: Foo, Heidi, et al.
Publicado: (2021)

Apathy as a determinant of health behaviors in older adults: Implications for dementia risk reduction
por: Harrison, Fleur, et al.
Publicado: (2023)

Correction: Grey Matter Correlates of Three Language Tests in Non-demented Older Adults
por: Zhang, Haobo, et al.
Publicado: (2014)

Grey Matter Correlates of Three Language Tests in Non-demented Older Adults
por: Zhang, Haobo, et al.
Publicado: (2013)

Differential blood miRNA expression in brain amyloid imaging-defined Alzheimer’s disease and controls
por: Wu, Helen Zong Ying, et al.
Publicado: (2020)

Instrumental Activities of Daily Living by Subjective and Objective Measures: The Impact of Depression and Personality
por: Numbers, Katya, et al.
Publicado: (2022)

Factors Predicting Reversion from Mild Cognitive Impairment to Normal Cognitive Functioning: A Population-Based Study
por: Sachdev, Perminder S., et al.
Publicado: (2013)

Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes
por: Liu, Yue, et al.
Publicado: (2021)

Lifespan Mental Activity Predicts Diminished Rate of Hippocampal Atrophy
por: Valenzuela, Michael J., et al.
Publicado: (2008)

Why aren't people with young onset dementia and their supporters using formal services? Results from the INSPIRED study
por: Cations, Monica, et al.
Publicado: (2017)

SAT-LB115 Metformin-Use Is Associated With Slowed Cognitive Decline and Reduced Incident Dementia in Older Adults With Type 2 Diabetes Mellitus: The Sydney Memory and Ageing Study
por: Samaras, Katherine, et al.
Publicado: (2020)

A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood
por: Jiang, Jiyang, et al.
Publicado: (2018)

GSK3B and MAPT Polymorphisms Are Associated with Grey Matter and Intracranial Volume in Healthy Individuals
por: Dobson-Stone, Carol, et al.
Publicado: (2013)

Upregulation of Glycolytic Enzymes, Mitochondrial Dysfunction and Increased Cytotoxicity in Glial Cells Treated with Alzheimer’s Disease Plasma
por: Jayasena, Tharusha, et al.
Publicado: (2015)

Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture
por: Zhang, Qian, et al.
Publicado: (2020)

Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia
por: Liu, Yue, et al.
Publicado: (2020)

Emergency department presentation and readmission after index psychiatric admission: a data linkage study
por: Li, Xue, et al.
Publicado: (2018)

Prevalence and incidence of physical health conditions in people with intellectual disability – a systematic review
por: Liao, Peiwen, et al.
Publicado: (2021)

Longitudinal changes in participant and informant reports of subjective cognitive complaints are associated with dementia risk
por: Numbers, Katya, et al.
Publicado: (2023)

Participant and informant memory-specific cognitive complaints predict future decline and incident dementia: Findings from the Sydney Memory and Ageing Study
por: Numbers, Katya, et al.
Publicado: (2020)

Networks of inflammation, depression, and cognition in aging males and females
por: Chalmers, Rebecca A., et al.
Publicado: (2022)

Early life affects late-life health through determining DNA methylation across the lifespan: A twin study
por: Li, Shuai, et al.
Publicado: (2022)

The Association between Pulse Wave Velocity and Cognitive Function: The Sydney Memory and Ageing Study
por: Singer, Joel, et al.
Publicado: (2013)

Harnessing brain and cognitive reserve for the prevention of dementia
por: Valenzuela, Michael, et al.
Publicado: (2009)

Comparison of Hippocampal Volume in Dementia Subtypes
por: Vijayakumar, Avinash, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_iq5bo4dsq7cc199rt52538jnid