Cytokine-Induced Loss of Glucocorticoid Function: Effect of Kinase Inhibitors, Long-Acting β2-Adrenoceptor Agonist and Glucocorticoid Receptor Ligands

Acting on the glucocorticoid receptor (NR3C1), glucocorticoids are widely used to treat inflammatory diseases. However, glucocorticoid resistance often leads to suboptimal asthma control. Since glucocorticoid-induced gene expression contributes to glucocorticoid activity, the aim of this study was t...

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Detalles Bibliográficos
Autores principales: Rider, Christopher F., Shah, Suharsh, Miller-Larsson, Anna, Giembycz, Mark A., Newton, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308083/
https://www.ncbi.nlm.nih.gov/pubmed/25625944
http://dx.doi.org/10.1371/journal.pone.0116773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308083/
https://www.ncbi.nlm.nih.gov/pubmed/25625944
http://dx.doi.org/10.1371/journal.pone.0116773

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